By Stefan H. E. Kaufmann, Bruce D. Walker
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Additional info for AIDS and Tuberculosis: A Deadly Liaison (Infection Biology Handbook Series)
J. , 72, 164–169. A. J. (2001) Analysis of total human immunodeﬁciency virus (HIV)-speciﬁc CD4( þ ) and CD8( þ ) T-cell responses: relationship to viral load in untreated HIV infection. J. , 75, 11983–11991. M. D. (2004) Persistent recognition of j21 j 1 HIV Immunology and Prospects for Vaccines 22 24 25 26 27 autologous virus by high-avidity CD8 T cells in chronic, progressive human immunodeﬁciency virus type 1 infection. J. , 78, 630–641. , Altfeld, M. D. (2003) Comprehensive epitope analysis of human immunodeﬁciency virus type 1 (HIV-1)-speciﬁc T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load.
6 Recent Advances in Animal Models: Reasons for Optimism completed in March 2007. The second Phase II trial of this study vaccine, Phambili (HVTN 503, Merck V520 Protocol 026), began in 2007 in South Africa, the goal being to determine whether the study vaccine used would prevent infection or reduce viral loads in an area where HIV subtype C is common. The STEP trial was successfully enrolled, and even expanded to include persons who were adenovirus seropositive, but was prematurely halted for futility based on an early review of incoming data.
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AIDS and Tuberculosis: A Deadly Liaison (Infection Biology Handbook Series) by Stefan H. E. Kaufmann, Bruce D. Walker